PRO 24X 7M

i'm not normally one for these all in one computers but this one seems a bit different in that it's using some highly capable parts and the upgrade paths appear to be easy to update.

• Windows 10 Home - MSI recommends Windows 10 Pro
• 23.8" IPS Grade Panel LED Backlight (1920*1080 FHD)
• Intel® Kaby Lake – U processors
• Support Intel® Optane Memory with Core™ i3 above processors (optional)
• Silent PRO Cooling System: Server Grade Thermal Module ensures a silent and stable operation with a longer life cycle.
• MSI Anti-Flicker technology protects users'eyes.
• MSI HDD Rapid Upgrade Design helps you to upgrade or maintain your 2.5” storage
• Dual LAN: the best way to back up your file / secure data and prevent the hacker (with MSI exclusive BIOS)
• Support TPM to offer a protected and encapsulated micro-controller security chip for safeguarding internal data.
• 178° wide viewing angle screen
• Featured MSI Super Charger technology that supports fast USB Sleep-and-Charge with auto-detection

check out the specs to see what i'm on about they really went in on this standalone offering -- it's not got the best graphics in the world but that's to be expect i guess when you try and get everything in a fairly skinny setup.

no reason you could not hook up an external 1080ti e-gpu solution over thunderbolt3/usb3.1 from one of the four ports.